phenobarbital sodium msds - An Overview

phenobarbital sodium msds - An Overview

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benzhydrocodone/acetaminophen and pentobarbital equally enhance sedation. Stay clear of or Use Alternate Drug. Restrict use to patients for whom alternative cure choices are inadequate

Contraindicated (one)pentobarbital will lessen the level or effect of doravirine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

Contraindicated (1)pentobarbital will lessen the extent or effect of lonafarnib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib is really a sensitive CYP3A4 substrate. Coadministration with powerful or moderate CYP3A4 inducers is contraindicated.

pentobarbital will reduce the level or effect of fentanyl transmucosal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead to some minimize in fentanyl plasma concentrations, deficiency of efficacy or, probably, improvement of a withdrawal syndrome inside of a affected person who may have created physical dependence to fentanyl.

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pentobarbital will reduce the extent or effect of fentanyl transdermal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead to some lessen in fentanyl plasma concentrations, deficiency of efficacy or, probably, advancement of a withdrawal syndrome inside a affected individual that has developed physical dependence to fentanyl.

Keep an eye on Closely (three)pentobarbital will lessen the level or effect of diazepam intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Powerful or moderate CYP3A4 inducers may perhaps check here maximize amount of diazepam elimination; hence, efficacy of diazepam can be lowered.

pentobarbital will lower the extent or effect of iloperidone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

pentobarbital will lessen the extent or effect of ketoconazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unknown.

pentobarbital will minimize the extent or effect of trazodone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will lessen the extent or effect of tacrolimus by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

pentobarbital will lower the level or effect of lopinavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

pentobarbital will lower the level or effect of dexamethasone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

fentanyl transdermal and pentobarbital equally boost sedation. Keep away from or Use Alternate Drug. Limit use to patients for whom alternative treatment options are insufficient